Dimethylformamide → HCID 20079645, compound

Participants

Reaction Steps

2.47 g of the product of Stage B were cooled to -60° C. in 20 ml of tetrahydrofuran and 9.2 ml of n-butyllithium were added. The mixture was stirred for 2 hours and 1.4 ml of dimethylformamide and 3 ml of tetrahydrofuran were added. The mixture was stirred for 30 minutes at -60° C., allowed to return to room temperature and the synthesis was continued as shown in Stage A to obtain 0.9 g of the expected product.

Provenance & Evidence