HCID 20079645, compound → HCID 20079660, compound

HRID 1654133Notes

Reaction equation

HRID 1654133 reaction equation
[Cl:1][C:2]1[CH:6]=[C:5]([CH:7]([F:9])[F:8])[S:4][C:3]=1[CH:10]=[O:11].[C:12]([Mg]Br)#[CH:13]>>[Cl:1][C:2]1[CH:6]=[C:5]([CH:7]([F:8])[F:9])[S:4][C:3]=1[CH:10]([OH:11])[C:12]#[CH:13]

Participants

3

Reactant 2

HCID 20079645HCID 20079645, compoundHCID 178418486HCID 178418486, compound

Product 1

HCID 20079660HCID 20079660, compound

Procedure

Using the procedure of Stage B of Preparation 2, 0.64 g of the product of Stage C above and 8.5 ml of ethynyl magnesium bromide were reacted to obtain 0.67 g of the expected product.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-5984dd6653df49358ea798c50e449ce0
Source dataset
uspto-grants-1995_04
Patent number
US05405865

Reaction notes

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