HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → N-(4-(4-(Ethyl(3-cyclopropylpropyl)amino)1-hydroxybutyl)phenyl)methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | N-(4-(4-(ethylamino)-1-hydroxybutyl)phenyl)methanesulfonamide | HCID 10779588 | — |
| Reactant | (3-Bromopropyl)cyclopropane | HCID 12734833 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-(4-(4-(Ethyl(3-cyclopropylpropyl)amino)1-hydroxybutyl)phenyl)methanesulfonamide | HCID 15294458 | — |
Reaction Steps
According to Procedure B (Example 17, Step IV), a stirred mixture of N-[4-[4-(ethylamino)-1-hydroxybutyl]phenyl]methanesulfonamide (Example 7, Step II) and sodium bicarbonate in acetonitrile was allowed to react will 1-bromo-3-cyclopropylpropane (Step IV) to give the titled product, a compound of Formula I'. The high resolution FAB mass spectrum had (M+H)+ at m/z 369. Theory for C19H33N2O3S: 369.2212; measured: 369.2207.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05405997 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-82a0f810140c4d61890782bb0471668f |
| Source note | uspto-grants-1995_04 |