HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → N-(4-(4-(Ethyl(4-cyclopropylbutyl)amino)-1-hydroxybutyl)phenyl)methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | N-(4-(4-(ethylamino)-1-hydroxybutyl)phenyl)methanesulfonamide | HCID 10779588 | — |
| Reactant | (4-Bromobutyl)cyclopropane | HCID 13789860 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-(4-(4-(Ethyl(4-cyclopropylbutyl)amino)-1-hydroxybutyl)phenyl)methanesulfonamide | HCID 15294459 | — |
Reaction Steps
According to Procedure B (Example 17, Step IV), a stirred mixture of N-[4-[4-(ethylamino)-1-hydroxybutyl]phenyl]methanesulfonamide Example 7, Step II) and sodium bicarbonate in acetonitrile was allowed to react with 1-bromo-4-cyclopropylbutane (Step IV) to give the titled product, a compound of Formula I'. The high resolution mass spectrum had M+ at m/z 382. Theory for C20H34N2O3S: 382.2290; measured: 382.2298.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05405997 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-9749a62dfd8a4b2d98f62f2bebd8ed06 |
| Source note | uspto-grants-1995_04 |