HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → N-(4-(4-(Ethyl(5-acetoxy-5-methylhexyl)amino)-1-hydroxybutyl)phenyl)methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | N-(4-(4-(ethylamino)-1-hydroxybutyl)phenyl)methanesulfonamide | HCID 10779588 | — |
| Reactant | 5-Acetoxy-1-bromo-5-methylhexane | HCID 20080111 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-(4-(4-(Ethyl(5-acetoxy-5-methylhexyl)amino)-1-hydroxybutyl)phenyl)methanesulfonamide | HCID 15294461 | — |
Reaction Steps
According to Procedure B (Example 17, Step IV), a stirred mixture of N-[4-[4-(ethylamino)-1-hydroxybutyl]phenyl]methanesulfonamide (Example 7, Step II) and sodium bicarbonate in acetonitrile was allowed to react with 5-acetoxy-1-bromo-5-methylhexane (Step V) to give the titled product, a compound of Formula I'. The mass spectrum had M+ at m/z 442.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05405997 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-128a7b65674645e889823941af658017 |
| Source note | uspto-grants-1995_04 |