Formaldehyde → HCID 178443615, compound

Participants

Reaction Conditions

Reaction Steps

Approximately 40.0 gm (0.3 mole) of tolyltriazole (commercially obtained from PMC Specialties Group, Inc. under the tradename Cobratec TT-100), 25.1 gm (0.31 mole) aqueous formaldehyde (37 wt. % solution in water), and 50 ml of methanol were charged into a 500 ml reactor equipped with a reflux condenser, thermometer, dropping funnel, and mechanical stirrer. The reaction mixture became homogeneous after stirring for about 5 minutes. Then 72.5 gm (0.3 mole) of bis(2-ethylhexyl)amine was slowly added to the reactor at a temperature less than 40° C. (moderate exotherm is observable). Thereafter, the mixture was heated to - 70° C. and maintained at reflux for 3 hrs. Then the reactants were heated at 110° C. during which methanol and water was azeotropically collected in the Dean-Stark trap. Finally, house vacuum was used to remove the trace amount of water at 110° C. for a half hour. A final filtration to remove possible unreacted tolyltriazole is optional. Small amounts of residual water could make the final product appear hazy. Approximately 115.3 gm of yellow liquid was recovered as desired product (>99% yield).

Provenance & Evidence