Hydrochloric Acid → HCID 131718964, compound

Participants

Reaction Steps

A solution of 7- (2-tert-butoxycarbonylamino-7-azaspiro[3.5 ]non-7-yl) 6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, ethyl ester (399 mg, 0.68 mmol) was hydrolyzed with hydrochloric acid to provide the title product, mp 270° C. (decomp.), 223 mg (0.45 mmol, 58% yield for two steps).

Provenance & Evidence