HCID 19882520, compound → HCID 20078491, compound

HRID 1654526Notes

Reaction equation

HRID 1654526 reaction equation
[NH:1]([CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][C:15]([O:17][CH3:18])=[O:16])=[CH:9][CH:8]=1)[C:2]([CH3:4])=[O:3]>C(O)C.[Ru](=O)=O>[NH:1]([CH2:5][CH2:6][CH:7]1[CH2:8][CH2:9][CH:10]([CH2:13][CH2:14][C:15]([O:17][CH3:18])=[O:16])[CH2:11][CH2:12]1)[C:2]([CH3:4])=[O:3]

Participants

4

Reactant 1

HCID 19882520HCID 19882520, compound

Product 1

HCID 20078491HCID 20078491, compoundYield 82%

Reagents, catalysts & solvents 2

HCID 82848Ruthenium dioxideCatalystHCID 702EthanolSolvent

Procedure

by the hydrogenation of methyl 3-[4-(2-acetaminoethyl)-phenyl ]-propionate in the presence of ruthenium dioxide in ethanol. Yield 82% of theory, semi-crystalline product.

Sources & evidence

ORD record
ord-dd22197a849e496298b27c96b1ec809b
Source dataset
uspto-grants-1995_04
Patent number
US05407951

Reaction notes

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