Methanol → HCID 178509248, compound

HRID 1654705Notes

Reaction equation

HRID 1654705 reaction equation
[NH2:1][C:2]1[N:3](C(=O)N)[N:4]=[CH:5][C:6]=1[C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:9][CH:8]=1.[OH-].[Na+].CO>O>[NH2:1][C:2]1[C:6]([C:7]2[CH:8]=[CH:9][C:10]([CH2:13][C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:11][CH:12]=2)=[CH:5][NH:4][N:3]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 14798Sodium HydroxideHCID 152804693-Amino-4-(4-benzylphenyl)-2-carbamoylpyrazole

Product 1

HCID 178509248HCID 178509248, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 3-amino-4-(4-benzylphenyl)-2-carbamoylpyrazole (1.00 g), sodium hydroxide (1.00 g), methanol (40 ml) and water (40 ml) was stirred under heating reflux for 3.5 hours, and ice-water was added.

Workup

  1. temperatureunder heating
  2. temperaturereflux for 3.5 hours

Sources & evidence

ORD record
ord-673487f6fa954e348e587102dd399921
Source dataset
uspto-grants-1995_04
Patent number
US05409928

Reaction notes

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