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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1654719Generated: October 25, 2026

Methanol → Benzoic acid, 4-ethyl-, methyl ester

https://huagongshe.com/reaction/1654719

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant4-Ethylbenzoic AcidHCID 12086—
ReactantThionyl ChlorideHCID 24386—
ProductBenzoic acid, 4-ethyl-, methyl esterHCID 23827—

Reaction Steps

A mixture of 4-ethylbenzoic acid (5.12 g), thionyl chloride (3.0 ml) and methanol (150 ml) was heated and refluxed. After 3 hours, the mixture was concentrated under reduced pressure to give methyl 4-ethylbenzoate (5.59 g). This product was used in the subsequent step without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05409928
Source datasetuspto-grants-1995_04
ORD IDord-82df3fa2d5ed477c9271a5c184240f1a
Source noteuspto-grants-1995_04