HCID 20076757, compound → HCID 20076707, compound

HRID 1654748Notes

Reaction equation

HRID 1654748 reaction equation
[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:27])=[C:11]([N:14]4[CH2:19][CH2:18][N:17](C(OC(C)(C)C)=O)[CH2:16][CH2:15]4)[CH:12]=3)[C:7](=[O:28])[C:6]([C:29](=[O:41])[CH:30]([C:36]([O:38][CH2:39][CH3:40])=[O:37])[C:31]([O:33][CH2:34][CH3:35])=[O:32])=[CH:5]2)[CH2:3][CH2:2]1.[ClH:42].C(OC(=O)C)C>>[ClH:42].[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:27])=[C:11]([N:14]4[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]4)[CH:12]=3)[C:7](=[O:28])[C:6]([C:29](=[O:41])[CH:30]([C:36]([O:38][CH2:39][CH3:40])=[O:37])[C:31]([O:33][CH2:34][CH3:35])=[O:32])=[CH:5]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 20076757HCID 20076757, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 20076707HCID 20076707, compoundYield 97%

Procedure

5.74 g of the compound obtained from Example 17 was dissolved in 100 ml of 10% HCl-ethylacetate solution, and the solution was stirred for 2 hours. The resulting solid was filtered, and then dried to obtain 4.95 g of the object compound

Workup

  1. filtrationThe resulting solid was filtered
  2. customdried

Sources & evidence

ORD record
ord-fd53cb05d4fd48b6a0705eb9a2e5f332
Source dataset
uspto-grants-1995_04
Patent number
US05409933

Reaction notes

Loading…