HCID 20076744, compound → HCID 20076762, compound

HRID 1654750Notes

Reaction equation

HRID 1654750 reaction equation
Cl.[CH:2]1([N:5]2[C:14]3[C:9](=[CH:10][C:11]([F:29])=[C:12]([N:16]4[CH2:20][CH2:19][CH:18]([NH:21]C(OC(C)(C)C)=O)[CH2:17]4)[C:13]=3[Cl:15])[C:8](=[O:30])[C:7]([C:31](=[O:37])[CH2:32][S:33]([CH3:36])(=[O:35])=[O:34])=[CH:6]2)[CH2:4][CH2:3]1>Cl.C(OC(=O)C)C>[ClH:15].[CH:2]1([N:5]2[C:14]3[C:9](=[CH:10][C:11]([F:29])=[C:12]([N:16]4[CH2:20][CH2:19][CH:18]([NH2:21])[CH2:17]4)[C:13]=3[Cl:15])[C:8](=[O:30])[C:7]([C:31](=[O:37])[CH2:32][S:33]([CH3:36])(=[O:35])=[O:34])=[CH:6]2)[CH2:4][CH2:3]1

Participants

3

Reactant 1

HCID 20076744HCID 20076744, compound

Product 1

HCID 20076762HCID 20076762, compoundYield 201.1%

Reagents, catalysts & solvents 1

HCID 21866389Hydrogen chloride-ethyl acetateSolvent

Procedure

5.4 g of the compound obtained from Example 32 was dissolved in 10% HCl-ethylacetate solution, and then stirred for 30 minutes. The resulting solid was filtered, and then dried to obtain 4.49 g of the object compound

Workup

  1. filtrationThe resulting solid was filtered
  2. customdried

Sources & evidence

ORD record
ord-9eac455ebb804475ad89f94c586dc7b5
Source dataset
uspto-grants-1995_04
Patent number
US05409933

Reaction notes

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