Water → N-2-(2,4-dichlorophenoxy)ethyl-N-n-octylamine

HRID 1654809Notes

Reaction equation

HRID 1654809 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:3]=1[O:4][CH2:5][CH2:6]Br.C(=O)([O-])[O-].[Na+].[Na+].[CH2:19]([NH2:27])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26].O>C(O)C>[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:3]=1[O:4][CH2:5][CH2:6][NH:27][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]

Participants

6

Reactant 4

HCID 962WaterHCID 8143OctylamineHCID 10340Sodium CarbonateHCID 1388811-(2-Bromoethoxy)-2,4-dichlorobenzene

Product 1

HCID 15278046N-2-(2,4-dichlorophenoxy)ethyl-N-n-octylamine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 20 ml of ethanol was dissolved 2.70 g (10.0 millimoles) of 2-(2,4-dichlorophenoxy)ethyl bromide, and 1.06 g (10.0 millimoles) of anhydrous sodium carbonate and 3.87 g (30.0 millimoles) of n-octylamine were added to the solution. The mixture was refluxed for 6 hours on an oil bath. After cooling, the reaction mixture was poured into 100 ml of water and extracted with 20 ml of chloroform three times.

Workup

  1. additionwere added to the solution
  2. temperatureThe mixture was refluxed for 6 hours on an oil bath
  3. temperatureAfter cooling
  4. extractionextracted with 20 ml of chloroform three times

Sources & evidence

ORD record
ord-493d59c8e1dc46c9bd754eceff79e085
Source dataset
uspto-grants-1995_04
Patent number
US05409957

Reaction notes

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