HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-3-benzyloxypyridine → HCID 178490392, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-3-benzyloxypyridine | HCID 90334 | — |
| Reactant | Ethyl 4-methoxyphenylacetimidate hydrochloride | HCID 12238406 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178490392 | HCID 178490392 | 16.5% |
Reaction Steps
A mixture of 2-amino-3-benzyloxypyridine (4.0 g, 20 mmol) and ethyl 4-methoxyphenylacetimidate hydrochloride (5.04 g, 22 mmol) in ethanol (80 ml) was heated under reflux for 2 hours. Evaporation of the solvent gave an oil which was purified by flash chromatography (chloroform/methanol) to give the product (1.27 g), m.p. 75°-78° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-06b35089617c4bc5861bcb5e9f1ad60a |
| Source note | uspto-grants-1995_04 |