HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 178491289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ethyl 2-phenylacetimidate hydrochloride | HCID 12218775 | — |
| Reactant | 3-[(2-Methylphenyl)methoxy]pyridin-2-amine | HCID 13825882 | — |
| Product | HCID 178491289 | HCID 178491289 | — |
Reaction Steps
A mixture of 2-amino-3-(2-methylbenzyloxy)pyridine (4.6 g, 20 mmol) and ethyl phenylacetimidate hydrochloride (4.39 g, 26 mmol) in ethanol (80 ml) was heated under reflux for 2 hours. Evaporation of the solvent gave an oil which was purified by flash chromatography (chloroform/methanol) to obtain the product (0.75 g), m.p. 188°-192° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-21f4667402f64acdb9ad0a48f61a3306 |
| Source note | uspto-grants-1995_04 |