Ethyl 2-phenylacetimidate hydrochloride → HCID 178426835, compound

Participants

Reaction Steps

A mixture of 2-amino-3-(2,6-dichlorobenzyloxy)-6-methyl-pyridine (5.66 g, 20 mmol) and ethyl phenylacetimidate hydrochloride (4.39 g, 22 mmol) in ethanol (80 ml) was heated under reflux for 2 hours. Evaporation of the solvent gave a residue which was purified by chromatography (silica, chloroform/methanol) and recrystallisation from ethanol/ether to obtain the product (1.34 g), m.p. 217°-218° C.

Provenance & Evidence