Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 2-phenylacetimidate hydrochloride → HCID 178426839, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 2-phenylacetimidate hydrochloride | HCID 12218775 | — |
| 반응물 | 2-Amino-3-(2,6-difluorobenzyloxy)-6-methylpyridine | HCID 20077021 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | HCID 178426839 | HCID 178426839 | 6.9% |
반응 단계
A mixture of 2-amino-3-(2,6-difluorobenzyloxy)-6-methyl-pyridine (5.0 g, 20 mmol) and ethyl phenylacetimidate hydrochloride (4.39 g, 22 mmol) in ethanol (80 ml) was heated under reflux for 2 hours. Evaporation of the solvent gave an oil which was purified by chromatography (silica, chloroform/methanol) and recrystallisation from ethanol/ether to obtain the product (0.56 g), m.p. 173°-177° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05409943 |
| 출처 데이터셋 | uspto-grants-1995_04 |
| ORD ID | ord-c596973933f0479ebdc3ea97b2ba706f |
| 출처 메모 | uspto-grants-1995_04 |