HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10265056, compound → HCID 178479195, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10265056 | HCID 10265056 | — |
| Reactant | Ethyl 2-phenylacetimidate hydrochloride | HCID 12218775 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178479195 | HCID 178479195 | 14.8% |
Reaction Steps
A mixture of 2-amino-3-(2,4-dichlorobenzyloxy)pyridine (5.07 g, 18.8 mmol) and ethyl phenylacetimidate hydrochloride (3.52 g, 25.8 mmol) in ethanol (150 ml) was heated under reflux for 2 hours. Evaporation of the solvent gave an oil which was purified by flash chromatography (dichloromethane/methanol) and trituration with ether to obtain the product (0.59 g), m.p. 185°-187° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-172a3a01759446c4b7a925adbe2aa3ee |
| Source note | uspto-grants-1995_04 |