HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 9993203, compound → HCID 178479197, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 9993203 | HCID 9993203 | — |
| Reactant | Ethyl 2-phenylacetimidate hydrochloride | HCID 12218775 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178479197 | HCID 178479197 | 6.3% |
Reaction Steps
A mixture of 2-amino-3-(2,5-dichlorobenzyloxy)pyridine (5.08 g, 18.8 mmol) and ethyl phenylacetimidate hydrochloride (3.52 g, 25.5 mmol) in ethanol (150 ml) was heated under reflux for 2 hours, then evaporated. Flash chromatography (dichloromethane/methanol) and trituration with ether gave the product (0.25 g), m.p. 191°-193° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-6b4b20d348b548b0b9529113ec3f03b8 |
| Source note | uspto-grants-1995_04 |