Ammonia → HCID 178510064, compound

HRID 1654865Notes

Reaction equation

HRID 1654865 reaction equation
[CH2:1]([O:8][C:9]1[C:10]([NH:15][C:16]([NH:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]#[N:26])=[CH:21][CH:20]=2)=S)=[N:11][CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:27]>>[CH2:1]([O:8][C:9]1[C:10]([NH:15][C:16]([NH:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]#[N:26])=[CH:21][CH:20]=2)=[NH:27])=[N:11][CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 20076927HCID 20076927, compound

Product 1

HCID 178510064HCID 178510064, compound

Procedure

To a stirring suspension of N-(3-benzyloxy-2-pyridyl)-N'-(4-cyanophenyl)thiourea (2 g, 0.0055 mol) in ammonia-saturated methanol (40 ml) was added yellow mercuric oxide (3 g, 0.014 mol). Stirring was continued for 20 h, then the mixture filtered through celite, and the solid washed several times with chloroform. The filtrate was evaporated to a white solid, which was triturated with ether. Yield 1.12 g (59%), m.p. 173°-175 ° C.

Workup

  1. filtrationthe mixture filtered through celite
  2. washthe solid washed several times with chloroform
  3. customThe filtrate was evaporated to a white solid, which
  4. customwas triturated with ether

Sources & evidence

ORD record
ord-da93103bf0d94503bfac225308ea1472
Source dataset
uspto-grants-1995_04
Patent number
US05409943

Reaction notes

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