HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 20077002, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 2-Amino-3-benzyloxypyridine | HCID 90334 | — |
| Reactant | 4-(Trifluoromethyl)phenyl isothiocyanate | HCID 137134 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20077002 | HCID 20077002 | — |
Reaction Steps
A mixture of 2-amino-3-benzyloxypyridine (2.34 g, 0.0117 mol), 4-trifluoromethylphenyl isothiocyanate (2.85 g, 0.014 mol) and toluene (10 ml) was refluxed for 3.5 hours, then cooled and treated with ether to induce crystallisation of the product. Yield 3.06 g (65%), m.p. 165°-167 ° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-88d79567295a4c798530cafbf6749e2a |
| Source note | uspto-grants-1995_04 |