HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 20076954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 1,2-Dichloro-4-isothiocyanatobenzene | HCID 23065 | — |
| Reactant | 2-Amino-3-benzyloxypyridine | HCID 90334 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20076954 | HCID 20076954 | — |
Reaction Steps
A mixture of 2-amino-3-benzyloxypyridine (2.14 g, 0.011 mol), 3,4-dichlorophenyl isothiocyanate (2.62 g, 0.013 mol) and toluene (10 ml) was refluxed for 3.5 hours, then cooled and treated with ether to induce crystallisation of the product. Yield 3.64 g (84%), m.p. 144°-146 ° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-3d0237acd30c4d5191792458cd6a5b68 |
| Source note | uspto-grants-1995_04 |