HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 20076949, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 4-Chlorophenyl isothiocyanate | HCID 16480 | — |
| Reactant | HCID 13825885 | HCID 13825885 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20076949 | HCID 20076949 | — |
Reaction Steps
A mixture of 2-amino-3-(2-chlorobenzyloxy)pyridine (1.81 g, 0.0077 mol), 4chlorophenyl isothiocyanate (1.59 g, 0.0094 mol) and toluene (10 ml) was refluxed for 2.5 hours, cooled and treated with diethyl ether to induce crystallisation of the product. Yield 2.54 g (90%), m.p. 177° 179 ° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-080bcb4f24a849859b0a3850634e72fc |
| Source note | uspto-grants-1995_04 |