HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 20076995, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 4-Chlorophenyl isothiocyanate | HCID 16480 | — |
| Reactant | HCID 20076935 | HCID 20076935 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20076995 | HCID 20076995 | — |
Reaction Steps
A mixture of 2-amino-3-(4-methylbenzyloxy)pyridine (1.45 g, 0.0068 mol), 4chlorophenyl isothiocyanate (1.38 g, 0.008 mol) and toluene (10 ml) was refluxed for 3.5 hours, then cooled and treated with diethyl ether to induce crystallisation of the product. Yield 1.8 g (70%), m.p. 145°-147 ° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-48344a17484442f2a9aa6526f30e7f64 |
| Source note | uspto-grants-1995_04 |