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HRID1654893

反应详情

EQUATION

反应方程式

HRID 1654893 的结构方程式

REACTANTS

反应物

3
结构：Cc1ccccc1
HCID1140

Toluene

C7H8

结构：O=[N+]([O-])c1ccc(N=C=S)cc1
HCID75044

Benzene, 1-isothiocyanato-4-nitro-

C7H4N2O2S

结构：Nc1ncccc1OCc1c(F)cccc1Cl
HCID10106270

未命名化合物

PRODUCTS

生成物

1
结构：O=[N+]([O-])c1ccc(NC(=S)Nc2ncccc2OCc2c(F)cccc2Cl)cc1
HCID20077035

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

A mixture of 2-amino-3-(2-chloro-6-fluorobenzyloxy)pyridine (7.01g, 0.028 mol), 4nitrophenyl isothiocyanate (5.31g, 0.03 mol) and toluene (50 ml) was heated under reflux for 2 hours, then cooled and treated with ether to induce crystallisation of the product. Yield 11.07 g (86%), m.p. 214° 215 ° C.

WORKUP

后处理

  1. temperaturewas heated
  2. temperatureunder reflux for 2 hours
  3. temperaturecooled
  4. customcrystallisation of the product
  5. customYield 11.07 g (86%), m.p. 214° 215 ° C.