HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 20076960, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 4-Chlorophenyl isothiocyanate | HCID 16480 | — |
| Reactant | HCID 20076964 | HCID 20076964 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20076960 | HCID 20076960 | — |
Reaction Steps
A mixture of 2-amino-3-(2-fluoro-4-methoxylbenzyloxy)pyridine (1.00 g, 0.004 mol), 4chlorophenyl isothiocyanate (0.68 g, 0.0048 mol) and toluene (10 ml) was refluxed for 3 hours, then cooled and treated with diethyl ether to induce crystallisation of the product. Yield0.86g(51%),m.p.138°-140° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-2717a490b8464a0e897f930456fd27e5 |
| Source note | uspto-grants-1995_04 |