Cyclohexane carboxylic acid chloride triethylamine → HCID 178418491, compound
Reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[CH:10]=[CH:9][C:8]([C@H:11]2[CH2:16][CH2:15][C@H:14]([OH:17])[CH2:13][CH2:12]2)=[CH:7][CH:6]=1)[CH3:3].[CH:18]1([C:24](Cl)=[O:25])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1.C(N(CC)CC)C>>[CH:18]1([C:24]([O:17][C@H:14]2[CH2:15][CH2:16][C@H:11]([C:8]3[CH:9]=[CH:10][C:5]([CH2:4][N:2]([CH3:1])[CH3:3])=[CH:6][CH:7]=3)[CH2:12][CH2:13]2)=[O:25])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1Participants
3
Procedure
from trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol and cyclohexane carboxylic acid chloride/triethylamine. White crystals.
Sources & evidence
- ORD record
- ord-65d0d248651b4777b9672b8046a54da0
- Source dataset
- uspto-grants-1998_03
- Patent number
- US05726205
Reaction notes
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