Methyl indole-7-carboxylate → HCID 54348549, compound

HRID 1655049Notes

Reaction equation

HRID 1655049 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[C:10]([O:12][CH3:13])=[O:11])[CH:3]=[CH:2]1.[N:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][C:15]=1[CH2:24][O:25][C:26]1[CH:33]=[CH:32][C:29]([CH2:30]Cl)=[CH:28][CH:27]=1>>[CH3:13][O:12][C:10]([C:8]1[CH:7]=[CH:6][CH:5]=[C:4]2[C:9]=1[N:1]([CH2:30][C:29]1[CH:28]=[CH:27][C:26]([O:25][CH2:24][C:15]3[CH:16]=[CH:17][C:18]4[C:23](=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:14]=3)=[CH:33][CH:32]=1)[CH:2]=[CH:3]2)=[O:11]

Participants

3

Reactant 2

HCID 676694Methyl indole-7-carboxylateHCID 147741632-(4-Chloromethylphenoxy)methylquinoline

Product 1

HCID 54348549HCID 54348549, compound

Procedure

This compound was prepared from methyl 7-indole carboxylate and 4-(quinolin-2-ylmethoxy)benzyl chloride (Example 1a) by the method described in Example 1b, part i. The residue was purified by chromatography on flash silica using petroleum spirit 40°-60° C./diethyl ether (2:1, 7:5) as eluent.

Workup

  1. customThe residue was purified by chromatography on flash silica
  2. custompetroleum spirit 40°-60° C./diethyl ether (2:1, 7:5)

Sources & evidence

ORD record
ord-5220a52e0c2c4758b4e886b6e4975a99
Source dataset
uspto-grants-1995_04
Patent number
US05410061

Reaction notes

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