methyl 1H-indole-5-carboxylate → HCID 53716446, compound
Reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][CH:9]=[CH:8]2)=[O:4].[N:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][C:15]=1[CH2:24][O:25][C:26]1[CH:27]=[C:28]([CH:31]=[CH:32][CH:33]=1)[CH2:29]Cl>>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[N:10]([CH2:29][C:28]1[CH:31]=[CH:32][CH:33]=[C:26]([O:25][CH2:24][C:15]3[CH:16]=[CH:17][C:18]4[C:23](=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:14]=3)[CH:27]=1)[CH:9]=[CH:8]2)=[O:4]Participants
3
Procedure
This compound was prepared from methyl-5-indole carboxylate and 3-(quinolin-2-ylmethoxy)benzyl chloride (Example 5a) by the method described in Example 1b, part i.
Sources & evidence
- ORD record
- ord-a66f4f3916764040865af5c7fe07c385
- Source dataset
- uspto-grants-1995_04
- Patent number
- US05410061
Reaction notes
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