methyl 1H-indole-5-carboxylate → HCID 86748648, compound

HRID 1655058Notes

Reaction equation

HRID 1655058 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([C:10]([O:12][CH3:13])=[O:11])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[N:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][C:15]=1[CH2:24][O:25][C:26]1[CH:33]=[CH:32][C:29]([CH2:30]Cl)=[CH:28][CH:27]=1>>[N:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][C:15]=1[CH2:24][O:25][C:26]1[CH:27]=[CH:28][C:29]([CH2:30][C:3]2[C:4]3[C:9](=[CH:8][CH:7]=[C:6]([C:10]([O:12][CH3:13])=[O:11])[CH:5]=3)[NH:1][CH:2]=2)=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 2737635methyl 1H-indole-5-carboxylateHCID 147741632-(4-Chloromethylphenoxy)methylquinoline

Product 1

HCID 86748648HCID 86748648, compound

Procedure

This compound was prepared from methyl indole-5-carboxylate and 4-(quinolin-2-ylmethoxy)benzyl chloride (Example 1a) by the method described in Example 12, part i, m.p. 179°-180° C.

Sources & evidence

ORD record
ord-33c0cb8ce7164ffa917b56d9b9f19afb
Source dataset
uspto-grants-1995_04
Patent number
US05410061

Reaction notes

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