Methyl indole-6-carboxylate → HCID 54339987, compound
Reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:10]([O:12][CH3:13])=[O:11])[CH:8]=2)[CH:3]=[CH:2]1.[N:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][C:15]=1[CH2:24][O:25][C:26]1[CH:27]=[C:28]([CH:31]=[CH:32][CH:33]=1)[CH2:29]Cl.COC(C1C=C2C(C(CC3C=CC(OCC4C=CC5C(=CC=CC=5)N=4)=CC=3)=CN2C)=CC=1)=O>>[CH3:13][O:12][C:10]([C:7]1[CH:8]=[C:9]2[C:4]([C:3]([CH2:29][C:28]3[CH:31]=[CH:32][CH:33]=[C:26]([O:25][CH2:24][C:15]4[CH:16]=[CH:17][C:18]5[C:23](=[CH:22][CH:21]=[CH:20][CH:19]=5)[N:14]=4)[CH:27]=3)=[CH:2][NH:1]2)=[CH:5][CH:6]=1)=[O:11]Participants
4
Procedure
This compound was prepared from methyl indole-6-carboxylate and 3-(quinolin-2-ylmethoxy)benzyl chloride (Example 5a) by the method described in Example 10, part ii.
Sources & evidence
- ORD record
- ord-cf4af01b457f4d55813c84a4d56e6422
- Source dataset
- uspto-grants-1995_04
- Patent number
- US05410061
Reaction notes
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