Indole-5-carbonitrile → HCID 20077529, compound

HRID 1655065Notes

Reaction equation

HRID 1655065 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH:7]=[CH:6]2)#[N:2].[N:12]1[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH:15]=[CH:14][C:13]=1[CH2:22][O:23][C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=1)[CH2:27]Cl.COC(C1C=C2C(C(CC3C=CC(OCC4C=CC5C(=CC=CC=5)N=4)=CC=3)=CN2C)=CC=1)=O>>[C:1]([C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH2:27][C:26]1[CH:29]=[CH:30][CH:31]=[C:24]([O:23][CH2:22][C:13]3[CH:14]=[CH:15][C:16]4[C:21](=[CH:20][CH:19]=[CH:18][CH:17]=4)[N:12]=3)[CH:25]=1)[CH:7]=[CH:6]2)#[N:2]

Participants

4

Reactant 3

HCID 27513Indole-5-carbonitrileHCID 145017062-(3-Chloromethylphenoxy)methylquinolineHCID 54440772HCID 54440772, compound

Product 1

HCID 20077529HCID 20077529, compound

Procedure

This compound was prepared from 5-cyanoindole and 3-(quinolin-2-ylmethoxy)benzyl chloride (Example 5a) by the method described in Example 16, part ii. The residue was crystallised from ethanol.

Workup

  1. customThe residue was crystallised from ethanol

Sources & evidence

ORD record
ord-323a495e18ab4a8d8777b2ed64fade1b
Source dataset
uspto-grants-1995_04
Patent number
US05410061

Reaction notes

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