Pyridine → HCID 19790752, compound

HRID 1655188Notes

Reaction equation

[Br:1][CH2:2][C:3]1[N:7]([C:8]2[C:13]([Cl:14])=[CH:12][C:11]([C:15]([F:18])([F:17])[F:16])=[CH:10][C:9]=2[Cl:19])[N:6]=[CH:5][C:4]=1[C:20]#[N:21].[N:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[Br-:1].[C:20]([C:4]1[CH:5]=[N:6][N:7]([C:8]2[C:13]([Cl:14])=[CH:12][C:11]([C:15]([F:18])([F:17])[F:16])=[CH:10][C:9]=2[Cl:19])[C:3]=1[CH2:2][N+:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)#[N:21]

Participants

Reactant 2

HCID 1049Pyridine

HCID 19020332HCID 19020332, compound

Product 1

HCID 19790752HCID 19790752, compound

Procedure

By the method of Example 5, Step E, 133 g (0.339 mole) of 5-bromomethyl-4-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-1H-pyrazole and 666 mL of pyridine were reacted, yielding 98 g of 1-[[4-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-1H-pyrazol-5-yl]methyl]pyridinium bromide. The nmr spectrum was consistent with the proposed structure.

Sources & evidence

ORD record: ord-56820e0a38a4433292daedbbc9600894
Source dataset: uspto-grants-1993_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05250504

Reaction notes

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