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HRID1655292

反应详情

EQUATION

反应方程式

HRID 1655292 的结构方程式

REACTANTS

反应物

1
结构：CCOC(=O)C=C[C@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)OC(C)(C)C
HCID54107369

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)CC[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)OC(C)(C)C
HCID53829475

Ethyl (γS)-γ-[[(1,1-dimethylethoxy)carbonyl]amino][1,1′-biphenyl]-4-pentanoate

C24H31NO4

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

(S)-4-(t-Butoxycarbonylamino)-5-(biphenyl-4-yl)-pentenoic acid ethyl ester (1.6 g), is dissolved in ethanol and hydrogenated under 48 psi for 2 hours with Pd/C catalyst. The mixture is filtered through Celite and the filtrate is concentrated in vacuo to yield (S)-4-(t-butoxycarbonylamino)-5-(biphenyl-4-yl)-pentanoic acid ethyl ester.

WORKUP

后处理

  1. filtrationThe mixture is filtered through Celite
  2. concentrationthe filtrate is concentrated in vacuo