o-Chloranil → 4-(7-Methoxynaphth-1-yl)-1-methylpiperidine

HRID 1655317Notes

Reaction equation

HRID 1655317 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][CH:9]=[C:10]2[CH:13]2[CH2:18][CH2:17][N:16]([CH3:19])[CH2:15][CH2:14]2)=[CH:5][CH:4]=1.ClC1C(=O)C(=O)C(Cl)=C(Cl)C=1Cl>C(O)C>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH:13]2[CH2:18][CH2:17][N:16]([CH3:19])[CH2:15][CH2:14]2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 73252o-ChloranilHCID 190962484-(3,4-Dihydro-7-methoxynaphth 1-yl)-1-methylpiperidine

Product 1

HCID 191052624-(7-Methoxynaphth-1-yl)-1-methylpiperidine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 11.5 g of the product from Example 15 and 23.1 g of tetrachloro-1,2-benzoquinone in solution in 600 ml of anhydrous ethyl alcohol is refluxed for 30 hours.

Workup

  1. temperatureis refluxed for 30 hours

Sources & evidence

ORD record
ord-3e6094c5ed694f53a63fbaea24d00858
Source dataset
uspto-grants-1993_10
Patent number
US05250544

Reaction notes

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