HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 9-(1,3-di-n-octanoyloxy-2 propoxymethyl)guanine HCl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 9-(1,3-Di-n-octanoyloxy-2-propoxymethyl)guanine | HCID 136332159 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 9-(1,3-di-n-octanoyloxy-2 propoxymethyl)guanine HCl | HCID 136332160 | — |
Reaction Steps
A twofold stoichiometric excess of 3% hydrogen chloride in methanol is added to a solution of 1.0 g. of 9-(1,3-di-n-octanoyloxy-2-propoxymethyl)guanine in 20 ml methanol. Diethyl ether is added until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized to give 9-(1,3-di-n-octanoyloxy-2-propoxymethyl)guanine hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05250535 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-5987b0489d054dad8ce04fdb94372b2c |
| Source note | uspto-grants-1993_10 |