HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic anhydride → HCID 14537017, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic anhydride | HCID 9845 | — |
| Reactant | HCID 14537015 | HCID 14537015 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 14537017 | HCID 14537017 | 89.7% |
Reaction Steps
2.0 g of 15β-cyano-1β-hydroxy-1α-methyl-5α-androstane-3,17-dione is stirred in 20 ml of glacial acetic acid with 6 ml of trifluoroacetic anhydride at room temperature. After 4 hours the solution is added to ice/water. The precipitated product is suctioned off, dissolved in ethyl acetate and washed with water. 1.7 g of 15β-cyano-1-methyl-5α-androst-1-ene-3,17-dione with a melting point of 193° C. is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05250712 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-2147678af6184bfd8913940bf5bfb285 |
| Source note | uspto-grants-1993_10 |