HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(tert-Butoxycarbonyl)-L-leucine methyl ester → tert-butyl N-(4-methyl-1-oxopentan-2-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(tert-Butoxycarbonyl)-L-leucine methyl ester | HCID 10879384 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Product | tert-butyl N-(4-methyl-1-oxopentan-2-yl)carbamate | HCID 546109 | — |
Reaction Steps
t-Butoxycarbonyl-L-leucine methyl ester was reduced with diisobutylaluminium hydride in an analogous manner to that described in Example 1 to give 2-t-butoxycarbonylamino-4-methyl-valeraldehyde, which was used directly in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05250517 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-b9598c68c91c485ebe1810fd72e62cc5 |
| Source note | uspto-grants-1993_10 |