HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Phenylalanine → 2,2,2-Trichloroethoxycarbonyl-L-phenylalanine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Phenylalanine | HCID 6140 | — |
| Reactant | 2,2,2-Trichloroethyl chloroformate | HCID 87063 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Methylenechloride Hexane | HCID 21226440 | — |
| Product | 2,2,2-Trichloroethoxycarbonyl-L-phenylalanine | HCID 13506134 | — |
Reaction Steps
L-phenylalanine was reacted with 2,2,2-trichloroethyl chloroformate in a 2N sodium bicarbonate solution, and after the usual working-up there was obtained the desired acid as crystals, melting point 126° (from methylene chloride/hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05250517 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-e91db11db4224026b1f0fc484be83637 |
| Source note | uspto-grants-1993_10 |