Sodium Methoxide → HCID 14801182, compound

HRID 1655803Notes

Reaction equation

HRID 1655803 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([Br:11])=[C:7]([Cl:12])[C:6]=1[CH2:13]Br)(=[O:4])=[O:3].[CH3:15][O-:16].[Na+]>CO>[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([Br:11])=[C:7]([Cl:12])[C:6]=1[CH2:13][O:16][CH3:15])(=[O:4])=[O:3]

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 14801181HCID 14801181, compound

Product 1

HCID 14801182HCID 14801182, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a suspension comprising 8.5 g of 4-bromo-2-bromomethyl-3-chlorophenyl methyl sulfone and 100 ml of methanol, 1.5 g of sodium methoxide (95%) was added under cooling with ice, and then the mixture was stirred at room temperature overnight.

Workup

  1. additionwas added
  2. temperatureunder cooling with ice

Sources & evidence

ORD record
ord-6963ee1e71df4a14abd3ef890b03ab87
Source dataset
uspto-grants-1993_10
Patent number
USRE034408

Reaction notes

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