Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,6-Di-tert-butylphenol | HCID 31405 | — |
| Reactant | 4-((6-(Acryloyloxy)hexyl)oxy)benzoic acid | HCID 3713565 | — |
| Reactant | HCID 54140554 | HCID 54140554 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Thionyl Chloride | HCID 24386 | — |
| Product | HCID 17976452 | HCID 17976452 | 59% |
Reaction Steps
2.9 g of 4-(6-acryloxyhexyloxy)benzoic acid was heat-refluxed for 2 hours in 10 ml of thionyl chloride in the presence of 2,6-di-t-butylphenol, followed by distilling-off of the thionyl chloride. Anhydrous THF and triethylamine were added to the reaction mixture, and a solution of 1.6 g of 2-methyl-2-propyloxyethyl 4-hydroxybenzoate in THF was added dropwise thereto at 0° C., followed by 4 hours of stirring at 50° C. The reaction mixture was subjected to extraction with ethyl acetate and column chromatography to obtain 1.8 g of the product. (Yield: 59 %)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05252251 |
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| Source dataset | uspto-grants-1993_10 |
|---|
| ORD ID | ord-0f895fc646e0490ab515f2ae6026c7d0 |
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| Source note | uspto-grants-1993_10 |
|---|
