4-Cyclohexylphenylhydrazine hydrochloride → 4-Cyclohexylphenylhydrazine

HRID 1655828Notes

Reaction equation

HRID 1655828 reaction equation
Cl.[CH:2]1([C:8]2[CH:13]=[CH:12][C:11]([NH:14][NH2:15])=[CH:10][CH:9]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1>[OH-].[Na+]>[CH:2]1([C:8]2[CH:9]=[CH:10][C:11]([NH:14][NH2:15])=[CH:12][CH:13]=2)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1

Participants

3

Reactant 1

HCID 187022954-Cyclohexylphenylhydrazine hydrochloride2×

Product 1

HCID 122501244-CyclohexylphenylhydrazineYield 77.7%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Conditions

Temperature
11 °C

Procedure

A suspension of 4-cyclohexylphenylhydrazine hydrochloride (Intermediate A) (41.4 g) and 3 N sodium hydroxide (120 ml) was stirred for 10 min at 0-22° C. The mixture was extracted with ether. The solvent was removed under vacuum to give 27 g of the titled compound, m.p. 115-116° C.

Workup

  1. extractionThe mixture was extracted with ether
  2. customThe solvent was removed under vacuum

Sources & evidence

ORD record
ord-94935e13be0d46b29d53570a21851fa8
Source dataset
uspto-grants-1993_10
Patent number
US05252426

Reaction notes

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