HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-(Benzyloxy)phenyl)hydrazine monohydrochloride → 4-Benzyloxyphenylhydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-(Benzyloxy)phenyl)hydrazine monohydrochloride | HCID 3016725 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Benzyloxyphenylhydrazine | HCID 561392 | 66.5% |
Reaction Steps
A suspension of 4-benzyloxyphenylhydrazine hydrochloride (Intermediate C) (25.0 g) and 1.0 equiv of sodium methoxide in methanol (110 ml) was refluxed for 30 min. The reaction was cooled and the precipitate was collected by vacuum filtration. The crude material was washed with water, and ether and dried under vacuum to give 14.2 g of the desired product, m.p. 101-103° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05252426 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-ccacdf40b0f441e6aa2b6b89f86a3df3 |
| Source note | uspto-grants-1993_10 |