1,2-Diamino-3,5-bis(trifluoromethyl)benzene → N-[5,7-Bis(trifluoromethyl)benzimidazol-2-yl]-1,2,3,4-tetrahydro-1-naphthylamine

Participants

Reaction Steps

The title compound was prepared from 3,5-bis(trifluoromethyl)-1,2-diaminobenzene and 1-isothiocyanato-1,2,3,4-tetrahydronaphthalene by Procedure D. The title compound was isolated by column chromatography as the free base and as a mixture of enantiomers (solid, dec. >240° C.). MS(ES+) m/z 400 ([M+1]+, 100).

Provenance & Evidence