Phenethyl bromide → HCID 131718211, compound

Participants

Reaction Steps

The amine salt (0.34 g, 1.4 mmol), phenethyl bromide (0.26 g, 1.4 mmol), and potassium carbonate (0.50 g) were heated at reflux in absolute ethanol (50 mL) for 48 hours. After cooling, the mixture was filtered and concentrated in vacuo. The crude product was purified by chromatography on silica gel, eluting with 10% methanol in chloroform, and concentrated in vacuo to yield a colorless oil (0.25 g, 51%). 1H NMR(300 MHz, CDCl3 /TMS, δ): 7.45-7.10(m,10H), 4.36(s,2H), 3.6(t,2H,J=6Hz), 3.04-1.20(m,15H).

Provenance & Evidence