HRID1655980

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID971

Oxalic acid

C2H2O4

结构：COc1cccc2c1CC(NCCCCN1C(=O)CC3(CCCCC3)C1=O)CO2

HCID18966575

未命名化合物

结构：COc1cccc2c1CC(NCCCCC1C(=O)NC(=O)C13CCCCC3)CO2.O=C(O)C(=O)O

HCID131718213

未命名化合物

PRODUCTS

生成物

结构：CCCN(CCCCC1C(=O)NC(=O)C12CCCCC2)C1COc2cccc(OC)c2C1.O=C(O)C(=O)O

HCID131718212

未命名化合物

PROCEDURE

实验过程

Using the procedure described in Example 10, but replacing the compound of Example 9 by the compound of Example 28, the product of the title is obtained. It is salified with oxalic acid.

WORKUP

后处理

customthe product of the title is obtained

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0c2ccd34d44041b2b314d7bf0b326e4f
来源数据集: uspto-grants-1993_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05252578
来源说明: uspto-grants-1993_10

反应 SMILES

CO[C:3]1[CH:12]=CC=C2[C:4]=1CC(NCCCCN1C(=O)C3(CCCCC3)CC1=O)CO2.[C:30]([OH:35])(=[O:34])[C:31]([OH:33])=[O:32].[CH3:36][O:37][C:38]1[CH:47]=[CH:46][CH:45]=[C:44]2[C:39]=1[CH2:40][CH:41]([NH:48][CH2:49][CH2:50][CH2:51][CH2:52][CH:53]1[C:57]3([CH2:62][CH2:61][CH2:60][CH2:59][CH2:58]3)[C:56](=[O:63])[NH:55][C:54]1=[O:64])[CH2:42][O:43]2.C(O)(=O)C(O)=O>>[C:30]([OH:35])(=[O:34])[C:31]([OH:33])=[O:32].[CH2:4]([N:48]([CH2:49][CH2:50][CH2:51][CH2:52][CH:53]1[C:57]2([CH2:58][CH2:59][CH2:60][CH2:61][CH2:62]2)[C:56](=[O:63])[NH:55][C:54]1=[O:64])[CH:41]1[CH2:40][C:39]2[C:44](=[CH:45][CH:46]=[CH:47][C:38]=2[O:37][CH3:36])[O:43][CH2:42]1)[CH2:3][CH3:12]