HCID 19789857, compound → HCID 178440621, compound

HRID 1656031Notes

Reaction equation

HRID 1656031 reaction equation
[Br:1][C:2]1[C:6]2[CH:7]=[C:8]([CH2:11][C:12]3[C:13]([CH2:26][O:27][CH3:28])=[N:14][N:15]([CH2:21][C:22]([F:25])([F:24])[F:23])[C:16]=3[CH2:17][CH2:18][CH2:19][CH3:20])[CH:9]=[CH:10][C:5]=2[O:4][C:3]=1[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[C:35]1[N:36]=[N:37][N:38](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[N:39]=1>CO.ClCCl>[Br:1][C:2]1[C:6]2[CH:7]=[C:8]([CH2:11][C:12]3[C:13]([CH2:26][O:27][CH3:28])=[N:14][N:15]([CH2:21][C:22]([F:24])([F:25])[F:23])[C:16]=3[CH2:17][CH2:18][CH2:19][CH3:20])[CH:9]=[CH:10][C:5]=2[O:4][C:3]=1[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[C:35]1[NH:39][N:38]=[N:37][N:36]=1

Participants

4

Reactant 1

HCID 19789857HCID 19789857, compound

Product 1

HCID 178440621HCID 178440621, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6344DichloromethaneSolvent

Procedure

From a solution of the Intermediate 14b (210 mg) in methanol (3 ml) and dichloromethane (1 ml) with dl-1-camphor-sulphonic acid (52 mg).

Sources & evidence

ORD record
ord-9ed0d162b52f44ea9498e3484a4910f6
Source dataset
uspto-grants-1993_10
Patent number
US05252593

Reaction notes

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