HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzene-1,2-diamine → N-(5-Fluorobenzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzene-1,2-diamine | HCID 164584 | — |
| Reactant | 1-Isothiocyanato-1,2,3,4-tetrahydronaphthalene | HCID 21393478 | — |
| Product | N-(5-Fluorobenzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine | HCID 68684304 | — |
Reaction Steps
The title compound was prepared from 4-fluorophenylenediamine and 1-isothiocyanato-1,2,3,4-tetrahydronaphthalene by Procedure D. The title compound was isolated by column chromatography as the free base and as a mixture of enantiomers (solid, mp 220-221° C.). MS(ES+) m/z 282 ([M+1]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07737167B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-b9d79720df6a4456b06914d23a4f9fdc |
| Source note | uspto-grants-2010_06 |