Potassium Chloride → HCID 19787631, compound

HRID 1656303Notes

Reaction equation

HRID 1656303 reaction equation
CN(C)C.[S:5]([C:9]1[CH:28]=[CH:27][CH:26]=[CH:25][C:10]=1[C:11]([N:13]1[C:21]2[C:16](=[CH:17][C:18]([N+:22]([O-:24])=[O:23])=[CH:19][CH:20]=2)[CH:15]=[N:14]1)=[O:12])([O-:8])(=[O:7])=[O:6].[Cl-].[K+:30]>CO.O>[K+:30].[S:5]([C:9]1[CH:28]=[CH:27][CH:26]=[CH:25][C:10]=1[C:11]([N:13]1[C:21]2[C:16](=[CH:17][C:18]([N+:22]([O-:24])=[O:23])=[CH:19][CH:20]=2)[CH:15]=[N:14]1)=[O:12])([O-:8])(=[O:7])=[O:6]

Participants

5

Reactant 2

HCID 4873Potassium Chloride2×HCID 19787627HCID 19787627, compound

Product 1

HCID 19787631HCID 19787631, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent2×

Procedure

To a suspension of 268.8 g (0.6 mole) of 1-(2-sulphonatobenzoyl)-5-nitroindazole trimethylamine salt in 540 ml of methanol and 360 ml of water was added at room temperature while stirring a saturated potassium chloride solution containing 134 g (1.8 mole) of potassium chloride in 400 ml of water. Then the suspension was stirred for another two hours. After waiting for 12 hours the precipitate was filtered off, washed with 480 ml of a water/methanol (1/1) mixture and finally dried. Yield: 217 g (94%); melting point>300° C.

Workup

  1. additionwas added at room temperature
  2. waitAfter waiting for 12 hours the precipitate
  3. filtrationwas filtered off
  4. washwashed with 480 ml of a water/methanol (1/1) mixture
  5. customfinally dried

Sources & evidence

ORD record
ord-95e5eab516d145f7991be983eb1af2e9
Source dataset
uspto-grants-1993_10
Patent number
US05254443

Reaction notes

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