Sulfuric acid magnesium salt (1:1) → HCID 19787933, compound

HRID 1656344Notes

Reaction equation

HRID 1656344 reaction equation
O=[C:2]1[CH2:7][CH2:6][N:5]([C:8]2[N:13]=[C:12]([C:14]([NH2:16])=[O:15])[CH:11]=[CH:10][N:9]=2)[CH2:4][CH2:3]1.[CH3:17][O:18][C:19]1[CH:28]=[CH:27][CH:26]=[CH:25][C:20]=1[O:21][CH2:22][CH2:23][NH2:24].S([O-])([O-])(=O)=O.[Mg+2]>ClCCl>[CH3:17][O:18][C:19]1[CH:28]=[CH:27][CH:26]=[CH:25][C:20]=1[O:21][CH2:22][CH2:23][N:24]=[C:2]1[CH2:7][CH2:6][N:5]([C:8]2[N:13]=[C:12]([C:14]([NH2:16])=[O:15])[CH:11]=[CH:10][N:9]=2)[CH2:4][CH2:3]1

Participants

5

Reactant 3

HCID 24083Sulfuric acid magnesium salt (1:1)HCID 17130052-(2-Methoxyphenoxy)ethyl amineHCID 19787938HCID 19787938, compound

Product 1

HCID 19787933HCID 19787933, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2.6 g (0.0118 mol) of 2-(4-oxopiperidin-yl)pyrimidine-4-carboxamide, 1.97 g (0.0188 mol) of 2-(2-methoxyphenoxy)ethylamine, 4.26 g (0.0354 mol) of magnesium sulphate and 152 ml of dichloromethane are introduced into a 500 ml flask and the mixture is stirred at room temperature for 24 hours.

Sources & evidence

ORD record
ord-c74f86071f1249f1a3c548243efdfd56
Source dataset
uspto-grants-1993_10
Patent number
US05254560

Reaction notes

Loading…